2022 non-steady state kidney function calculator

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With the 2009 CKD-EPI equation having fallen out of favor (1), it is high time to provide an updated non-steady state kidney function calculator (2, 3):

Non-steady state GFR is estimated with the EKFC formula (4) and the 2021 CKD-EPI refit (5). It also provides 2012 KDIGO AKI categories (6) with standard 7 day and 48 hours creatinine values (7).

For reference values for creatinine generation rate and total body water for adults see (3, 8).

References

  1. Delgado C, Baweja M, Crews D et al. A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease. J Am Soc Nephrol. 2021; ASN.2021070988.

  2. http://www.swissnephro.org/blog/2021/3/2/the-non-steady-state-ckd-epi-calculator

  3. Buchkremer F, Bock A, Segerer S. The non-steady state CKD-EPI calculator. Clin Kidney J. 2021; 14(7): 1853-1856.

  4. Pottel H, Björk J, Courbebaisse M et al. Development and Validation of a Modified Full Age Spectrum Creatinine-Based Equation to Estimate Glomerular Filtration Rate : A Cross-sectional Analysis of Pooled Data. Ann Intern Med. 2021; 174(2): 183-191.

  5. Inker LA, Eneanya ND, Coresh J et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med. 2021

  6. https://kdigo.org/guidelines/acute-kidney-injury/

  7. Buchkremer F, Segerer S. A Simple Method to Remove Timing Bias From the Kidney Disease: Improving Global Outcomes Definition and Classification of Acute Kidney Injury. Kidney Int Rep. 2021; 6(6): 1747-1748.

  8. Buchkremer F, Segerer S. Body Surface Area, Creatinine Excretion Rate, and Total Body Water: Reference Data for Adults in the United States. Kidney Med. 2021; 3(2): 312-313.

Calculator, Creametrics, AKI, NephrologyFlorian Buchkremer